FDA Recall Open, Classified

BECKMAN COULTER BICARBONATE REF: OSR6137 OSR6237 OSR6637 OSR6x37 Bicarbonate is a system reagent for the quantitative determination of Bicarbonate in human serum and plasma on Beckman Coulter AU analyzers.

Recall: Z-0997-2026 · Initiated October 14, 2025

Recall

Recall Number
Z-0997-2026
Event Number
97842
Firm
Beckman Coulter Ireland, Inc. Lismeehan O'Callaghan'S Mills Ireland
FEI Number
1000206808
Product Code
KHS
Status
Open, Classified
Root Cause
Nonconforming Material/Component
Initiated
October 14, 2025
Posted
December 23, 2025

Description

BECKMAN COULTER BICARBONATE REF: OSR6137 OSR6237 OSR6637 OSR6x37 Bicarbonate is a system reagent for the quantitative determination of Bicarbonate in human serum and plasma on Beckman Coulter AU analyzers.

Reason

Bicarbonate reagent may generate falsely high Bicarbonate results due to interference with Lactate Dehydrogenase (LDH) in the test sample.

Action

On 10/14/2025, the firm sent via US Postal and email an "URGENT MEDICAL DEVICE RECALL" Letter to customers informing them that complaints have been received for elevated results generated using Bicarbonate reagent when there are high levels of lactate Dehydrogenase (LDH) in the test samples. Beckman Coulter has investigated and confirmed that the lots listed above of Bicarbonate reagent may generate Bicarbonate results that are biased high due to interference with LDH in the test sample. Customers are instructed to: "Discontinue use and dispose all Bicarbonate OSR6x37 lots listed in Table A in the ISSUE section of this letter, following their laboratory protocols and local regulations. Contact their local Beckman Coulter representative for replacement or re-imbursement. "For Bicarbonate OSR6x37 lots listed in Table B in the ISSUE section if elevated LDH levels are suspected, please assess results in conjunction with patient s LDH values. "Share the content of this letter with their laboratory and/or Medical Director to evaluate the requirement for a retrospective review of Bicarbonate results for neonatal patients and patients with elevated LDH levels. o Complete the attached Replacement Order Form and email to [email protected] or fax to (866) 294-7850 OR o Call Client Services at (800) 526-3821 For questions, contact Customer Support Center. "From Beckman Coulter's website: http://www.beckmancoulter.com "By phone: call 1-800-854-3633 in the United States.

Distribution

Worldwide - U.S. Nationwide distribution in the states of AK, AL, AR, AZ, CA, CO, CT, DC, DE, FL, GA, Guan, HI, IA, ID, IL, IN, KS, KY, LA, MA, MD, ME, MI, MN, MO, MS, MT, NC, ND, NE, NH, NJ, NM, NV, NY, OH, OK, OR, PA, PR, RI, SC, SD, TN, TX, UT, VA, WA, WI, WV, and WY. The countries of Argentina, Brazil, Canada, Ecuador, Ireland, Mexico, Netherlands, Panama, Taiwan, and Province of China.

Quantity

36,981 reagents (U.S.-35,320, O.U.S.-1,661)