FDA PMA FDA Class 3 Approved 🇺🇸 United States

Mr-Guided Focused Ultrasound System

PMA: P150038 · Supplement: S036 · Decision Oct 8, 2024
Classifications
1
FEI Numbers
4
Registration Numbers
4

Basic Information

Device Name
Mr-Guided Focused Ultrasound System
Trade Name
Exablate Neuro, Exablate Prime, Exablate Transcranial MRgFUS, Exablate Model 4000, Exablate Neuravive
PMA Number
P150038
Supplement Number
S036
Device Class
FDA Class 3
Product Code
POH
Generic Name
MR-guided focused ultrasound system
Medical Specialty
Unknown
Advisory Committee
Neurology
Decision
Approved
Decision Code
APPR
Decision Date
October 8, 2024
Date Received
April 17, 2024
Supplement Type
Normal 180 Day Track
Supplement Reason
Change Design/Components/Specifications/Material
Expedited Review
N

Advisory Committee Statement

approval for the Exablate Model 4000 Type 1.1 System software version 9.0.1 to be compatible with Philips 1.5 Tesla (T) and 3.0 T magnetic resonance imaging (MRI) scanners, and the hardware and labeling were modified accordingly as a result of this proposed change. In addition, the P150038/S036 application proposed the following changes to the subject device:• Expanded tractography support, to allow the display of overlapping anatomical structures.• Added baseline thermometry averaging (compared to approved baseline calculation using the last “cold phase” image), for enhanced sound-to-noise ratio (SNR), within approved specifications.• Added a visual indication of auto-calibration process bar and tracking planning scan acquisition.• Enhanced cavitation monitoring mechanism requirements, to further improve the robustness of the monitoring to sporadic noises and reduce false cavitation alerts.• Added additional thermometry protocols for GE and Siemens MRI scanners as additional options for users.

Classifications

This FDA Pre-Market Approval entry is associated with 1 FDA classification via its product code.

Product Code Device Name
POH Mr-Guided Focused Ultrasound System