FDA PMA FDA Class 3 Approved 🇺🇸 United States

Aortic Valve, Prosthesis, Percutaneously Delivered

PMA: P130021 · Supplement: S174 · Decision Aug 27, 2025
Classifications
1
FEI Numbers
0
Registration Numbers
0

Basic Information

Device Name
Aortic Valve, Prosthesis, Percutaneously Delivered
Trade Name
Evolut PRO+ System, Evolut FX System, Evolut FX+ System
PMA Number
P130021
Supplement Number
S174
Device Class
FDA Class 3
Product Code
NPT
Generic Name
Aortic valve, prosthesis, percutaneously delivered
Medical Specialty
Unknown
Advisory Committee
Cardiovascular
Decision
Approved
Decision Code
APPR
Decision Date
August 27, 2025
Date Received
February 28, 2025
Supplement Type
Panel Track
Supplement Reason
Labeling Change - Indications/instructions/shelf life/tradename
Expedited Review
N
Docket Number
25M-3437

Advisory Committee Statement

Approval for the Evolut PRO+ System, Evolut FX System, Evolut FX+ System for expanding the indications to include the treatment of patients with a failed trascatheter aortic valve who are at high or greater risk of mortality from open surgical therapy. This device is indicated for use in patients with symptomatic heart disease due to failure (stenosed, insufficient, or combined) of a surgical or transcatheter bioprosthetic aortic valve who are judged by a heart team, including a cardiac surgeon, to be at high or greater risk for open surgical therapy (i.e., predicted risk of surgical mortality >8% at 30 days, based on the STS risk score and other clinical co-morbidities unmeasured by the STS risk calculator).

Classifications

This FDA Pre-Market Approval entry is associated with 1 FDA classification via its product code.

Product Code Device Name
NPT Aortic Valve, Prosthesis, Percutaneously Delivered