FDA PMA FDA Class 3 Approved 🇺🇸 United States

System, Colorectal Neoplasia, Dna Methylation And Hemoglobin Detection

PMA: P130017 · Supplement: S066 · Decision Nov 24, 2025
Classifications
1
FEI Numbers
0
Registration Numbers
0

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Basic Information

Device Name
System, Colorectal Neoplasia, Dna Methylation And Hemoglobin Detection
Trade Name
Cologuard®
PMA Number
P130017
Supplement Number
S066
Device Class
FDA Class 3
Product Code
PHP
Generic Name
System, colorectal neoplasia, DNA methylation and hemoglobin detection
Medical Specialty
Unknown
Advisory Committee
Pathology
Decision
Approved
Decision Code
APPR
Decision Date
November 24, 2025
Date Received
September 11, 2025
Supplement Type
Real-Time Process
Supplement Reason
Labeling Change - Indications/instructions/shelf life/tradename
Expedited Review
N

Advisory Committee Statement

The Center for Devices and Radiological Health (CDRH) of the Food and Drug Administration (FDA) has completed its review of your premarket approval application (PMA) supplement, which qualified for review under the Real-Time Review Program. Your supplement requested to modify the in-process sample stability of the hemoglobin sample from 7 days to 14 days at 2 to 8°C, and additional minor labeling changes. Based upon the information submitted, the PMA supplement is approved. You may begin commercial distribution of the device as modified by your PMA supplement in accordance with the conditions described below. Although this letter refers to your product as a device, please be aware that some approved products may instead be combination products.

Classifications

This FDA Pre-Market Approval entry is associated with 1 FDA classification via its product code.

Product Code Device Name
PHP System, Colorectal Neoplasia, Dna Methylation And Hemoglobin Detection