Product Code: PRB FDA class 2 21 CFR 864.1865

Cervical Intraepithelial Neoplasia (Cin) Test System

Pathology

The Cervical Intraepithelial Neoplasia (CIN) Test System is a qualitative immunohistochemistry (IHC) test that assesses p16INK4a protein in formalin-fixed, paraffin-embedded (FFPE) cervical punch biopsy tissues as an adjunct to H&E staining, intended to improve consistency in the diagnosis of cervical intraepithelial neoplasia. It is classified as FDA Class 2 under 21 CFR 864.1865 in the Pathology specialty, requiring 510(k) premarket notification. Diagnosis must be based on H&E-stained slides and other clinical and laboratory information. Product code PRB; not an implant and not life-sustaining.

510(k)s
2
FEI Numbers
1
Registration Numbers
1
Unique Applicants
1
Years Active
5

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Basic Information

Product Code
PRB
Device Class
FDA class 2
Regulation Number
864.1865
Medical Specialty
Pathology
Review Panel
PA
Submission Type
1

Device Characteristics

GMP Exempt
Implant
Life Sustain/Support
Third Party
Summary Malfunction Reporting

Definition

The p16 CIN test system is a qualitative immunohistochemistry (IHC) test to assess the p16INK4a protein in formalin-fixed, paraffin-embedded (FFPE) cervical punch biopsy tissues. It is indicated as an adjunct to examination of hematoxylin and eosin (H&E) stained slide(s), to improve consistency in the diagnosis of CIN. Diagnosis of CIN presence or level should be based on H&E stained slide(s) and other clinical and laboratory test information.

510(k) Clearance History

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Related 510(k) Clearances

This FDA classification is associated with 2 510(k) clearances via K numbers.

K Number Device Name
K212176 CINtec Histology
DEN160019 CINtec Histology (50 tests), CINtec Histology (250 tests)

FEI Numbers

This FDA classification entry is associated with 1 FEI number. Click on an entry to view related FDA registrations.

Registration Numbers

This FDA classification entry is associated with 1 registration number. Click on an entry to view related FDA registrations.