Description of Event or Problem · 1
THE ALBUMIN QUOTIENT WAS ELEVATED IN THREE OF FIVE PATIENTS, AND OGB WAS NEGATIVE IN ALL FIVE. THEREFORE, PLASMAPHERESIS WITH ALBUMIN WAS INITIATED AND PERFORMED ON ALTERNATE DAYS ON THE HYPOTHESIS OF AN AUTOIMMUNE CNS INVOLVEMENT FOR BOTH MRI POSITIVE AND NEGATIVE CASES. THE CLINICAL PICTURE IN CASE 3 WORSENED, WITH REFRACTORY FEVER AROUND 40.5 ¿C AND FERRITIN LEVELS THAT PEAKED AT 15,669 NG/ML. CARDIAC ARREST DEVELOPED AND CPR WAS UNSUCCESSFUL. THERE IS NO STANDARD/APPROVED THERAPY FOR THIS DISEASE; UNUSUAL DISEASE PRESENTATION. SEVERE SARS-COV-2 (COVID-19) INFECTION HAS THE POTENTIAL FOR A HIGH MORTALITY RATE. IN THIS PAPER, WE REPORT THE RESULTS OF PLASMAPHERESIS TREATMENT IN A SERIES OF SEVERELY ILL PATIENTS WITH COVID-19-RELATED AUTOIMMUNE MENINGOENCEPHALITIS IN THE INTENSIVE CARE UNIT (ICU). ARTICLE URL: HTTPS://PUBMED.NCBI.NLM.NIH.GOV/32389697/JOURNAL: BRAIN, BEHAVIOR, AND IMMUNITY. PUBLICATION YEAR: 2020; PUBLISHED AUTHORS: DOGAN L, KAYA D, SARIKAYA T, ZENGIN R, DINCER A, AKINCI IO, AFSAR N.