Cortisol Assay kit CLIA

Primary DI

06974521004004

Basic UDI-DI Code

B-06974521004004

Reference

SUPM065036

Device Types

Single use

Regulation

Eu Ivdd

Classification

Eu Ivd General

Status

On The Market

Manufacturer

Shenzhen Superbio Technology Co.,Ltd.

This kit is used for in vitro quantitative detection of cortisol in human serum, plasma and (or) urine. It can be used to diagnose whether adrenal gland, hypophysis and hypothalamus function well. Cortisol (hydrocortisone) is the foremost glucocorticoid of human body, which is of great importance for maintaining many physiological functions. Similar to other glucocorticoids, cortisol is synthesized by a common cholesterol precursor in the adrenal cortex-zona fasciculata. About 90% of cortisol in blood circulation binds to corticosteroid binding globulin (CBG) and albumin and then is transported. Only a little free cortisol reacts with their receptors. The most important physiological action of cortisol is to improve the blood glucose level (improve gluconeogenesis and glycolysis), and resist inflammation and immunosuppressive reaction. Cortisol is synthesized and secreted by adrenal gland and regulated by negative feedback of hypothalamus-hypophysis-adrenal cortex-axis. If the concentration of cortisol in the blood decreases, the hypothalamus will secret corticotropin releasing hormone (CRH). CRH can promote the hypophysis to release adrenocorticotrophic hormone (ACTH). ACTH can promote adrenal synthesis and cortisol cecretion. Cortisol has a negative feedback effect on hypophysis and hypothalamus.

Other on-the-market devices with the same classification (Eu Ivd General) and regulation (EU IVDD).