SPECIFIC PROTEINS - OTHER

Primary DI

D-02B0024YP

Basic UDI-DI Code

B-02B0024YP

Reference

3H001

Device Types

Single use

Regulation

Eu Ivdd

Classification

Eu Ivd General

Status

On The Market

Manufacturer

Changsha Sinocare Inc.

Serum amyloid A (SAA) Reagent Kit is intended to quantitatively determine SAA concentration in human serum. Clinically, it is mainly used as an inflammatory index. As an acute phase protein, its concentration in blood can increase dramatically within a few hours and rise to 1000 times the initial concentration during inflammatory, infectious and non-infectious diseases. SAA is correlated with HDL and can regulate the metabolism of high-density lipoprotein (HDL) during inflammation. A particularly important characteristic of SAA is that its degradation products can be deposited in different organs in the form of amyloid fibrils, which is a serious complication in chronic inflammatory diseases; Elevated SAA is also seen in atherosclerosis, diabetic nephropathy, acute myocardial infarction, coronary heart disease, and chronic kidney disease. SAA and C reactive protein (CRP) share similar effects on evaluating inflammation, predicting its activity and treatment, while SAA detection is more valid in diagnosis for patients with viral infection, renal transplantation rejection (especially those treated with immunosuppressive therapy) and patients with cystic fibrosis treated with adrenocortical hormone compared with CRP. It has been found that SAA is more closely related to disease activity in cases of arthritis, and the detection of CRP and SAA at the same time can improve the diagnostic sensitivity of infection.

Other on-the-market devices with the same classification (Eu Ivd General) and regulation (EU IVDD).